THE STUDY
THE CONCEPT
THE MODEL
THE RESEARCH
THE REPLICATION
THE CONTACT
THE AUTHOR |
AUTHOR |
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| THE AUTHOR |
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What is the background and experience of the author of this study? The author, George P. Sakalosky, Ph.D., biophysicist and radiation specialist, began molecular modeling in 1957 to develop a means for identifying energy absorption sites in DNA. He was awarded a doctoral degree in 1975 following the completion of interdisciplinary, intercollegiate doctoral courses in biochemistry, biophysics, learning theory, and neurochemistry at M.I.T. (at M.I.T., using his new model, he presented a paper entitled, “The Physicochemical Action of Lithium as a Psychopharmacological Agent in the Treatment of Manic Illness” ), at Tufts University School of Medicine, at Boston University, and at Boston College where he was awarded a Ph.D. These studies concluded with a doctoral thesis entitled, “Proton Symmetry: Its Implications for Learning Theory -- A Biophysics Concept.” |
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| His early interest in cancer was related to radiation energy absorption in DNA, especially that which caused cancer. He began a radiobiology study at RCA in New Jersey where in 1957 he co-authored a book for the U.S. Air Force entitled, “A Radiobiology Guide.” In gathering information for the book, he found that cancer researchers had serious difficulties identifying the primary intramolecular radiation-absorption cancer-producing site in DNA. This spurred his interest in developing a molecular model that could be used for this purpose. |
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| Dr. Sakalosky joined the General Nuclear Engineering Corporation, Dunedin, Florida, in 1959, where he served as Technical Writer and co-Editor of the USAEC-sponsored publication Power Reactor Technology and where he worked with the nuclear engineers and served, preparing the publication, under Dr. Joseph Dietrick, one of the brilliant designers of the first cores of nuclear electric power reactors. He then joined Martin Marietta in Baltimore, MD, working with the engineers who designed Systems Nuclear Power (SNAP) units. In 1963, he joined the Division of Reactor Development, U.S. Atomic Energy Commission, in Maryland and in Washington, D.C. At the USAEC, he served as a Staff Assistant to the Chairman of the Commission and as a staff member of the U.S. Delegation to the Third United Nations International Conference on the Peaceful Uses of Atomic Energy , in 1964, in Geneva, Switzerland (As a member of the Staff, United States Delegation, he served the conference as Reports Officer and prepared the final report entitled, “Atoms for Peace Conference, 1964” ). |
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| Dr. Sakalosky organized and held at M.I.T. the first national conference on ENERGY. He conducted subsequent conferences on ENERGY held at Boston College and at the Universities of Michigan and Michigan State. He also organized and held (in conjunction with the 1978 World’s Fair in Knoxville, TN) the first international conference on ENERGY conducted in the Conference Center in Gatlinburg, TN. He has worked in various companies in the radiation and nuclear-electric power fields, including Curtiss-Wright Research; Boston Edison Co.; Consumers Power Co. in Michigan; Southern Science Co.; NUS; Enercon; and, at Sequoyah Fuels where he was Manager of the Health Physics Radiation Department and conducted daily inspections of the operation and safety of the company's uranium-hexafluoride-producing system. He organized and conducted successfully the company’s first Emergency Response to a depicted tornado emergency held under the observation of the USNRC. Dr. Sakalosky developed a program, in the late 1990's, to synthesize and test at the M.D. Anderson Cancer Center in Houston his three potential cancer therapeutic compounds, via a small company, sponsored financially by Magalen O. Bryant of Middleburg, VA, for this purpose, called Alchemy International where he served as Vice President, Research & Development. Other similar cancer tests using the compounds were conducted in North Carolina and in Alabama. The compounds were also tested in Frederick, Maryland, against HIV. |
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| Dr. Sakalosky conducted technology-related courses for students at the University of Arizona, in Tucson and at the University of Tennessee, Knoxville, TN. In April, 1978, he presented a paper -- at the New Mexico Academy of Science conference co-sponsored by the American Association for Advancement of Science -- entitled, “Developmental Features of a New and Critical Structural Aberration in DNA: Production of an Ozonide in a Thymine Nucleoside as a Suggested Mechanism for Carcinogenesis.” He served as President of General Biophysics, Inc., a biotechnology company developing new programs in molecular modeling aimed at cancer pharmacology. He also served as a consultant on health physics, radiation protection, and radiological emergency preparedness, with SAIC Corporation, Oak Ridge, TN. He also worked for the Oak Ridge Institute for Science and Education (ORISE) and, while there, was a member of the U.S. Department of Energy Traveling Lecture Program. |
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| Dr. Sakalosky is a charter member of the American Society for Photobiology (ASP) and has been a member of the European Society for Photobiology. He was appointed Research Professor at Boston College for the college's 1988 to 1991 academic years and was Nonresident Lecturer in Biophysics at the School of Public Health, University of Michigan. He has co-authored two radiation publications with Dr. A.P. Jacobson, Professor or Radiological Health, University of Michigan, entitled, “Radiation in Medicine and Industry,” (Following the nuclear accident at TMI, this publication was distributed by the State of Pennsylvania to students in all the high schools of Pennsylvania) and “Submolecular DNA, Radiation, and the Genesis of Cancer,” and he has authored a book called “The Predictor Model” which provides many of the details of his molecular modeling studies. His other publications are entitled, “Christmas Crucible,” “Seasons without End,” and “E=I.” |
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Considered as his final work, Dr. Sakalosky developed the Periodic Symmetry Concept and the Symmetry Analytical Model as molecular modeling tools primarily for the study of carcinogenesis; and, from this development, he designed and provided information for the synthesis of his three potential anti-cancer, anti-AIDS, compounds, Compound B, Compound K, and Compound Z. |
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He makes his home with his wife, Judith, in Gatlinburg, Tennessee. |
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